Globally, cervical cancer is the second most common cancer in women and the third most frequent cause of cancer death (IARC, WHO 2002). Human papillomavirus (HPV) is considered the primary driving force behind malignant transformation of cervical cells, nearly all cervical cancer is due to HPV.
HPV is a small, nonenveloped, double-stranded DNA virus, with a genome of approximately 8,000 nucleotides. Of the 120 known human papilloma viruses, 51 species and three subtypes infect the genital mucosa.15 are classified as high-risk types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68, 73, and 82). Among them, HPV types 16 and 18 have been regarded as the genotypes most closely associated with progression to cervical cancer. HPV-16 is the most carcinogenic and is associated with approximately 60% of all cervical cancers, while HPV-18 accounts for approximately 10% to 15% of cervical cancers.
Fig.1 Cervical cancer caused by human papillomavirus
HPV test is a screening test for cervical cancer, which will not tell you whether you have this cancer. Instead, the test will detect whether there is HPV in the system and detect the type of HPV. Nucleic acid (DNA) testing by PCR has become a standard, noninvasive method for determining the presence of a cervical HPV infection.
The research team of Creative Biogene has rich experience in the fields of molecular biology and gene diagnosis. Creative Biogene can provide you with HPV-DNA detection of pathological tissues, mucus and secretions based on PCR technology.
| Service items | Material requirements |
| Cervical sample | 3 mL solution |
| Swab sample | 3 mL solution |
Results from a Human papillomavirus (HPV) can help determine whether cervical cells are infected with a high-risk type of HPV and identify abnormal changes in cervical cells, and results from your HPV test will come back as either positive or negative.
You can customize the HPV test by phone or email, and our colleagues will reply your inquiry within three working days.